PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24013224-0 2014 Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis. Doxorubicin 95-106 TNF superfamily member 10 Homo sapiens 148-153 24013224-3 2014 Chemotherapeutic agents, such as doxorubicin have been shown to act synergistically with TRAIL, but the exact mechanisms of actions are poorly understood. Doxorubicin 33-44 TNF superfamily member 10 Homo sapiens 89-94 24013224-4 2014 In this study, we performed high-throughput small interfering RNA screening and genome-wide gene expression profiling on doxorubicin-treated U1690 cells to explore novel mechanisms underlying doxorubicin-TRAIL synergy. Doxorubicin 121-132 TNF superfamily member 10 Homo sapiens 204-209 24013224-4 2014 In this study, we performed high-throughput small interfering RNA screening and genome-wide gene expression profiling on doxorubicin-treated U1690 cells to explore novel mechanisms underlying doxorubicin-TRAIL synergy. Doxorubicin 192-203 TNF superfamily member 10 Homo sapiens 204-209