PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23946483-5 2013 One, it decreases the level of Rap1 activity as measured by GTP loading and the coupling of Rap1 to RapL, a Rap1 effector that couples Rap1 GTP loading to integrin activation. Guanosine Triphosphate 60-63 RAP1A, member of RAS oncogene family Homo sapiens 31-35 23946483-5 2013 One, it decreases the level of Rap1 activity as measured by GTP loading and the coupling of Rap1 to RapL, a Rap1 effector that couples Rap1 GTP loading to integrin activation. Guanosine Triphosphate 140-143 RAP1A, member of RAS oncogene family Homo sapiens 31-35 23946483-5 2013 One, it decreases the level of Rap1 activity as measured by GTP loading and the coupling of Rap1 to RapL, a Rap1 effector that couples Rap1 GTP loading to integrin activation. Guanosine Triphosphate 140-143 RAP1A, member of RAS oncogene family Homo sapiens 92-96 23946483-5 2013 One, it decreases the level of Rap1 activity as measured by GTP loading and the coupling of Rap1 to RapL, a Rap1 effector that couples Rap1 GTP loading to integrin activation. Guanosine Triphosphate 140-143 RAP1A, member of RAS oncogene family Homo sapiens 92-96 23946483-5 2013 One, it decreases the level of Rap1 activity as measured by GTP loading and the coupling of Rap1 to RapL, a Rap1 effector that couples Rap1 GTP loading to integrin activation. Guanosine Triphosphate 140-143 RAP1A, member of RAS oncogene family Homo sapiens 92-96 23946483-7 2013 These two actions, decreased GTP loading and decreased membrane localization, are related, as the translocation of Rap1-GTP into the cytoplasm is associated with its increased GTP hydrolysis and inactivation. Guanosine Triphosphate 29-32 RAP1A, member of RAS oncogene family Homo sapiens 115-119 23946483-7 2013 These two actions, decreased GTP loading and decreased membrane localization, are related, as the translocation of Rap1-GTP into the cytoplasm is associated with its increased GTP hydrolysis and inactivation. Guanosine Triphosphate 120-123 RAP1A, member of RAS oncogene family Homo sapiens 115-119