PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2393852-0 1990 Lorglumide and loxiglumide inhibit gastrin-stimulated DNA synthesis in a rat tumoral acinar pancreatic cell line (AR42J). loxiglumide 15-26 gastrin Rattus norvegicus 35-42 2393852-5 1990 We found that all antagonists displaced 125I-labeled gastrin binding, with the following order of potencies: L364,718 greater than CR1409 greater than CR1505 greater than proglumide. loxiglumide 151-157 gastrin Rattus norvegicus 53-60 2393852-6 1990 Furthermore, the 50% inhibitory concentration of CR1409 and CR1505 to inhibit gastrin stimulated ornithine decarboxylase activity (an early event involved in cell proliferation) and [3H]thymidine incorporation were in agreement with their constants of inhibition (Ki) on gastrin binding. loxiglumide 60-66 gastrin Rattus norvegicus 78-85 2393852-6 1990 Furthermore, the 50% inhibitory concentration of CR1409 and CR1505 to inhibit gastrin stimulated ornithine decarboxylase activity (an early event involved in cell proliferation) and [3H]thymidine incorporation were in agreement with their constants of inhibition (Ki) on gastrin binding. loxiglumide 60-66 gastrin Rattus norvegicus 271-278