PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23876794-4	2013	In the present study we revealed NuFkappaBeta as the upstream mediator involved in Btg2 transcription in response to cell stress challenges such as serum deprivation and oxidative stress i.e. H2O2, TPA or doxorubicin treatments in several cell lines.	Hydrogen Peroxide	192-196	BTG anti-proliferation factor 2	Homo sapiens	83-87	
23876794-4	2013	In the present study we revealed NuFkappaBeta as the upstream mediator involved in Btg2 transcription in response to cell stress challenges such as serum deprivation and oxidative stress i.e. H2O2, TPA or doxorubicin treatments in several cell lines.	Tetradecanoylphorbol Acetate	198-201	BTG anti-proliferation factor 2	Homo sapiens	83-87	
23876794-4	2013	In the present study we revealed NuFkappaBeta as the upstream mediator involved in Btg2 transcription in response to cell stress challenges such as serum deprivation and oxidative stress i.e. H2O2, TPA or doxorubicin treatments in several cell lines.	Doxorubicin	205-216	BTG anti-proliferation factor 2	Homo sapiens	83-87	
23876794-5	2013	We observed close interrelation between generation of reactive oxygen species (ROS), enhanced IkappaBalpha degradation, nuclear translocation of NuFkappaBeta (p65/RelA) and the significant increase of Btg2 expression independent of p53 status.	Reactive Oxygen Species	54-77	BTG anti-proliferation factor 2	Homo sapiens	201-205	
23876794-8	2013	Generation of ROS was the common event mediating NuFkappaBeta activation and Btg2 transcription.	Reactive Oxygen Species	14-17	BTG anti-proliferation factor 2	Homo sapiens	77-81	
23876794-9	2013	Furthermore, PKC activation was also found to be a critical factor mediating ROS-mediated signals to NFkappaB pathway that culminate on Btg2 regulation, and specifically PKC-delta was responsible for this regulation under oxidative stress.	Reactive Oxygen Species	77-80	protein kinase C delta	Homo sapiens	13-16	
23876794-9	2013	Furthermore, PKC activation was also found to be a critical factor mediating ROS-mediated signals to NFkappaB pathway that culminate on Btg2 regulation, and specifically PKC-delta was responsible for this regulation under oxidative stress.	Reactive Oxygen Species	77-80	nuclear factor kappa B subunit 1	Homo sapiens	101-109	
23876794-9	2013	Furthermore, PKC activation was also found to be a critical factor mediating ROS-mediated signals to NFkappaB pathway that culminate on Btg2 regulation, and specifically PKC-delta was responsible for this regulation under oxidative stress.	Reactive Oxygen Species	77-80	BTG anti-proliferation factor 2	Homo sapiens	136-140	
23876794-10	2013	However, serum deprivation-associated ROS generation bypassed PKC activation for induction of Btg2 expression via NFkappaB activation.	Reactive Oxygen Species	38-41	BTG anti-proliferation factor 2	Homo sapiens	94-98	
23876794-10	2013	However, serum deprivation-associated ROS generation bypassed PKC activation for induction of Btg2 expression via NFkappaB activation.	Reactive Oxygen Species	38-41	nuclear factor kappa B subunit 1	Homo sapiens	114-122	
23876794-11	2013	The present data imply that oxidative stress upregulates Btg2 expression via ROS-PKC-NuFkappaBeta cascade, independent of p53 status that in turn could be involved in mediating various biological phenotypes depending on the cellular context.	Reactive Oxygen Species	77-80	BTG anti-proliferation factor 2	Homo sapiens	57-61	
23876794-11	2013	The present data imply that oxidative stress upregulates Btg2 expression via ROS-PKC-NuFkappaBeta cascade, independent of p53 status that in turn could be involved in mediating various biological phenotypes depending on the cellular context.	Reactive Oxygen Species	77-80	protein kinase C delta	Homo sapiens	81-84