PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23861949-0	2013	Celastrol inhibits lipopolysaccharide-stimulated rheumatoid fibroblast-like synoviocyte invasion through suppression of TLR4/NF-kappaB-mediated matrix metalloproteinase-9 expression.	celastrol	0-9	toll like receptor 4	Homo sapiens	120-124	
23861949-6	2013	Furthermore, our results revealed that celastrol inhibited the transcriptional activity of MMP-9 by suppressing the binding activity of NF-kappaB in the MMP-9 promoter, and suppressed the TLR4/MyD88/NF-kappaB pathway.	celastrol	39-48	toll like receptor 4	Homo sapiens	188-192	
23861949-8	2013	In conclusion, celastrol might inhibit FLS migration and invasion induced by LPS by suppressing TLR4/NF-kappaB-mediated MMP-9 expression, providing a theoretical foundation for the clinical treatment of RA with celastrol.	celastrol	15-24	toll like receptor 4	Homo sapiens	96-100	
23861949-8	2013	In conclusion, celastrol might inhibit FLS migration and invasion induced by LPS by suppressing TLR4/NF-kappaB-mediated MMP-9 expression, providing a theoretical foundation for the clinical treatment of RA with celastrol.	celastrol	211-220	toll like receptor 4	Homo sapiens	96-100