PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2373171-0 1990 The relative roles of the glutathione redox cycle and catalase in the detoxification of H2O2 by cultured rabbit lens epithelial cells. Hydrogen Peroxide 88-92 catalase Oryctolagus cuniculus 54-62 2373171-1 1990 The relative roles of the glutathione redox cycle and catalase in the detoxification of H2O2 were investigated in cultured rabbit lens epithelial cells. Hydrogen Peroxide 88-92 catalase Oryctolagus cuniculus 54-62 2373171-8 1990 In contrast, cells with completely inhibited catalase but with an unimpaired glutathione redox cycle suffered few damaging effects from a 3-hr exposure to 0.025 mM H2O2. Hydrogen Peroxide 164-168 catalase Oryctolagus cuniculus 45-53 2373171-9 1990 When lens cells were pulsed with a single challenge of 0.5 mM H2O2, both the glutathione redox cycle and catalase were found to be essential for survival of the cells. Hydrogen Peroxide 62-66 catalase Oryctolagus cuniculus 105-113 2373171-12 1990 The cause of cell death following inhibition of catalase appeared to be related to an inability of the cells to remove peroxide from the culture medium, at a rapid rate, following the H2O2-pulse. Hydrogen Peroxide 184-188 catalase Oryctolagus cuniculus 48-56