PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23730215-6	2013	We have also found that a single mutation of the Tyr(644) or Tyr(664) residue of the C terminus of NPM-ALK to phenylalanine decreases significantly, but does not completely abolish, the association between NPM-ALK and IGF-IR.	Tyrosine	49-52	ALK receptor tyrosine kinase	Homo sapiens	103-106	
23730215-6	2013	We have also found that a single mutation of the Tyr(644) or Tyr(664) residue of the C terminus of NPM-ALK to phenylalanine decreases significantly, but does not completely abolish, the association between NPM-ALK and IGF-IR.	Tyrosine	49-52	ALK receptor tyrosine kinase	Homo sapiens	210-213	
23730215-6	2013	We have also found that a single mutation of the Tyr(644) or Tyr(664) residue of the C terminus of NPM-ALK to phenylalanine decreases significantly, but does not completely abolish, the association between NPM-ALK and IGF-IR.	Tyrosine	61-64	ALK receptor tyrosine kinase	Homo sapiens	103-106	
23730215-6	2013	We have also found that a single mutation of the Tyr(644) or Tyr(664) residue of the C terminus of NPM-ALK to phenylalanine decreases significantly, but does not completely abolish, the association between NPM-ALK and IGF-IR.	Tyrosine	61-64	ALK receptor tyrosine kinase	Homo sapiens	210-213	
23730215-7	2013	The purpose of this study was to determine whether the dual mutation of Tyr(644) and Tyr(664) abrogates the association and interactions between NPM-ALK and IGF-IR.	Tyrosine	72-75	ALK receptor tyrosine kinase	Homo sapiens	149-152	
23730215-7	2013	The purpose of this study was to determine whether the dual mutation of Tyr(644) and Tyr(664) abrogates the association and interactions between NPM-ALK and IGF-IR.	Tyrosine	85-88	ALK receptor tyrosine kinase	Homo sapiens	149-152	
23730215-10	2013	Importantly, we found that the dual mutation of Tyr(644) and Tyr(664) diminishes the oncogenic effects of NPM-ALK, including its ability to induce anchorage-independent colony formation and to sustain cellular transformation, proliferation, and migration.	Tyrosine	48-51	ALK receptor tyrosine kinase	Homo sapiens	110-113	
23730215-10	2013	Importantly, we found that the dual mutation of Tyr(644) and Tyr(664) diminishes the oncogenic effects of NPM-ALK, including its ability to induce anchorage-independent colony formation and to sustain cellular transformation, proliferation, and migration.	Tyrosine	61-64	ALK receptor tyrosine kinase	Homo sapiens	110-113	
23730215-11	2013	Furthermore, the association between NPM-ALK and IGF-IR through Tyr(644) and Tyr(664) appears to contribute to maintaining the stability of NPM-ALK protein.	Tyrosine	64-67	ALK receptor tyrosine kinase	Homo sapiens	41-44	
23730215-11	2013	Furthermore, the association between NPM-ALK and IGF-IR through Tyr(644) and Tyr(664) appears to contribute to maintaining the stability of NPM-ALK protein.	Tyrosine	64-67	ALK receptor tyrosine kinase	Homo sapiens	144-147	
23730215-11	2013	Furthermore, the association between NPM-ALK and IGF-IR through Tyr(644) and Tyr(664) appears to contribute to maintaining the stability of NPM-ALK protein.	Tyrosine	77-80	ALK receptor tyrosine kinase	Homo sapiens	144-147