PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2369894-4 1990 These same single amino acid substitutions enhanced the affinity of the thrombomodulin-thrombin complex for the substrate at 3 mM calcium 3-(Gly-substitution) to 6-(Phe-substitution) fold, either without influencing kcat (Gly-substitution) or with a 2.5-fold decrease of kcat. Glycine 141-144 coagulation factor II, thrombin Homo sapiens 87-95 2369894-4 1990 These same single amino acid substitutions enhanced the affinity of the thrombomodulin-thrombin complex for the substrate at 3 mM calcium 3-(Gly-substitution) to 6-(Phe-substitution) fold, either without influencing kcat (Gly-substitution) or with a 2.5-fold decrease of kcat. Glycine 222-225 coagulation factor II, thrombin Homo sapiens 87-95