PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23640035-0	2013	Neutralization of interleukin-1 beta attenuates silica-induced lung inflammation and fibrosis in C57BL/6 mice.	Silicon Dioxide	48-54	interleukin 1 beta	Mus musculus	18-36	
23640035-2	2013	Interleukin-1 beta (IL-1beta) plays an important role in silica-induced lung inflammation, but the mechanisms that underlie the influence of IL-1beta on the progression of silicosis remain unclear.	Silicon Dioxide	57-63	interleukin 1 beta	Mus musculus	0-18	
23640035-2	2013	Interleukin-1 beta (IL-1beta) plays an important role in silica-induced lung inflammation, but the mechanisms that underlie the influence of IL-1beta on the progression of silicosis remain unclear.	Silicon Dioxide	57-63	interleukin 1 beta	Mus musculus	20-28	
23640035-3	2013	In this study, the role of IL-1beta in silica-induced inflammation and fibrosis was evaluated by administering a suspension of 2.5-mg silica dust, either with or without 40 mug anti-mouse IL-1beta monoclonal antibody (mAb), to the lungs of male C57BL/6 mice.	Silicon Dioxide	39-45	interleukin 1 beta	Mus musculus	27-35	
23640035-4	2013	Silica + anti-IL-1beta mAb-treated mice showed the depletion of IL-1beta as well as the attenuation of inflammation, as evaluated in the bronchoalveolar lavage fluid (BALF) and histological sections from 1 to 84 days after silica exposure.	Silicon Dioxide	0-6	interleukin 1 beta	Mus musculus	14-22	
23640035-4	2013	Silica + anti-IL-1beta mAb-treated mice showed the depletion of IL-1beta as well as the attenuation of inflammation, as evaluated in the bronchoalveolar lavage fluid (BALF) and histological sections from 1 to 84 days after silica exposure.	Silicon Dioxide	0-6	interleukin 1 beta	Mus musculus	64-72	
23640035-4	2013	Silica + anti-IL-1beta mAb-treated mice showed the depletion of IL-1beta as well as the attenuation of inflammation, as evaluated in the bronchoalveolar lavage fluid (BALF) and histological sections from 1 to 84 days after silica exposure.	Silicon Dioxide	223-229	interleukin 1 beta	Mus musculus	14-22	
23640035-6	2013	The real-time PCR and pathology results showed that the neutralization of IL-1beta attenuated silica-induced fibrosis by inhibiting the gene expression of transforming growth factor-beta 1, collagen I and fibronectin.	Silicon Dioxide	94-100	interleukin 1 beta	Mus musculus	74-82	
23640035-8	2013	In conclusion, the present study suggests that the neutralization of IL-1beta attenuates silica-induced inflammation and fibrosis by inhibiting other inflammatory and fibrogenic mediators and modulating the Th1/Th2 balance.	Silicon Dioxide	89-95	interleukin 1 beta	Mus musculus	69-77