PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 235760-1 1975 Tyrosine hydroxylase (EC 1.14.16.2), the enzyme catalyzing the rate-limiting step in catecholamine biosynthesis, was localized by electron microscopy within noradrenergic neurons of the nucleus locus coeruleus of the rat brain with a specific antibody to tyrosine hydroxylase labeled by the peroxidase-antiperoxidase immunohistochemical method. Catecholamines 85-98 tyrosine hydroxylase Rattus norvegicus 0-20