PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23467537-10 2011 After treatment with PS-341, a proteasome inhibitor, the IkappaB degradation was inhibited, IkappaB expression increased, NF-kappaB and P-gp expression decreased in a time dependent manner. Bortezomib 21-27 nuclear factor kappa B subunit 1 Homo sapiens 122-131 23467537-11 2011 Compared to DNR group, the NF-kappaB p65 activity of DNR+PS-341 group was decreased. Bortezomib 57-63 nuclear factor kappa B subunit 1 Homo sapiens 27-36 23467537-14 2011 The mechanism may be that bortezomib decreases the degradation of IkappaB and the expression of NF-kappaB and P-gp, therefore induces the apoptosis of multi-drug resistant cells. Bortezomib 26-36 nuclear factor kappa B subunit 1 Homo sapiens 96-105