PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23462281-5 2013 Multiple studies have evaluated the connection between thiamine and PD pathology, and candidate pathways involve the transcription factor Sp1, p53, Bcl-2, caspase-3, tyrosine hydroxylase, glycogen synthase kinase-3beta, vascular endothelial growth factor, advanced glycation end products, nuclear factor kappa B, mitogen-activated protein kinase, and the reduced form of nicotinamide adenine dinucleotide phosphate. Thiamine 55-63 tumor protein p53 Homo sapiens 143-146