PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23430957-8	2013	Thus, HDAC8 plays an important role in the modulation of SOCS1 and SOCS3 by curcumin.	Curcumin	76-84	histone deacetylase 8	Homo sapiens	6-11	
23430957-11	2013	Finally, curcumin markedly inhibited HDAC activities and decreased HDAC8 levels in primary MPN cells.	Curcumin	9-17	histone deacetylase 8	Homo sapiens	67-72	
23430957-12	2013	Taken together, our data uncover a regulatory mechanism of SOCS1 and SOCS3 through inhibition of HDAC activity (especially HDAC8) by curcumin.	Curcumin	133-141	histone deacetylase 8	Homo sapiens	123-128