PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23415873-7 2013 Furthermore, curcumin increased the expression of the ER stress associated transcriptional factors XBP-1, cleaved p50ATF6alpha and C/EBP homologous protein (CHOP) in human CD4+ and Jurkat T cells. Curcumin 13-21 DNA damage inducible transcript 3 Homo sapiens 131-155 23415873-7 2013 Furthermore, curcumin increased the expression of the ER stress associated transcriptional factors XBP-1, cleaved p50ATF6alpha and C/EBP homologous protein (CHOP) in human CD4+ and Jurkat T cells. Curcumin 13-21 DNA damage inducible transcript 3 Homo sapiens 157-161 23415873-8 2013 In PHA-activated T cells, curcumin further enhanced PHA-induced CHOP expression and reduced the expression of the anti-apoptotic protein Bcl-2. Curcumin 26-34 DNA damage inducible transcript 3 Homo sapiens 64-68 23415873-9 2013 Finally, curcumin treatment induced apoptotic cell death in activated T cells via eliciting an excessive ER stress response, which was reversed by the ER-stress inhibitor 4-phenylbutyric acid or transfection with CHOP-specific siRNA. Curcumin 9-17 DNA damage inducible transcript 3 Homo sapiens 213-217