PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23382808-0	2013	Functional roles of the non-catalytic calcium-binding sites in the N-terminal domain of human peptidylarginine deiminase 4.	Calcium	38-45	peptidyl arginine deiminase 4	Homo sapiens	94-122	
23382808-5	2013	Asn153 and Asp176 are directly coordinated with Ca3 and indirectly coordinated with Ca5 via a water molecule.	Water	94-99	carbonic anhydrase 5A	Homo sapiens	84-87	
23382808-7	2013	Asp168 is the direct ligand for Ca5, and Ca5 coordination by Glu252 is mediated by two water molecules.	Water	87-92	carbonic anhydrase 5A	Homo sapiens	41-44	
23382808-11	2013	In addition, the results of urea-induced denaturation for the N153, D155, D157 and D179 series mutants further suggest that the binding of Ca(2+) ions in the N-terminal Ca(2+)-binding site stabilizes the overall conformational stability of PAD4.	Urea	28-32	peptidyl arginine deiminase 4	Homo sapiens	240-244