PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23376588-3	2013	In the present study, we aimed to investigate whether the pro-inflammatory cytokines interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) released by microglia, could affect cellular iron transportation in primary cultured ventral mesencephalic (VM) neurons.	Iron	203-207	interleukin 1 beta	Mus musculus	85-102	
23376588-3	2013	In the present study, we aimed to investigate whether the pro-inflammatory cytokines interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) released by microglia, could affect cellular iron transportation in primary cultured ventral mesencephalic (VM) neurons.	Iron	203-207	interleukin 1 beta	Mus musculus	104-112	
23376588-4	2013	The results showed that IL-1beta or TNF-alpha treatment led to increased ferrous iron influx and decreased iron efflux in these cells, due to the upregulation of divalent metal transporter 1 with the iron response element (DMT1+IRE) and downregulation of ferroportin1 (FPN1).	Iron	81-85	interleukin 1 beta	Mus musculus	24-32	
23376588-4	2013	The results showed that IL-1beta or TNF-alpha treatment led to increased ferrous iron influx and decreased iron efflux in these cells, due to the upregulation of divalent metal transporter 1 with the iron response element (DMT1+IRE) and downregulation of ferroportin1 (FPN1).	Iron	107-111	interleukin 1 beta	Mus musculus	24-32	
23376588-4	2013	The results showed that IL-1beta or TNF-alpha treatment led to increased ferrous iron influx and decreased iron efflux in these cells, due to the upregulation of divalent metal transporter 1 with the iron response element (DMT1+IRE) and downregulation of ferroportin1 (FPN1).	Iron	107-111	interleukin 1 beta	Mus musculus	24-32	
23376588-7	2013	Further experiments demonstrated that IL-1beta and TNF-alpha release was remarkably enhanced by iron load in activated microglia triggered by lipopolysaccharide or 1-methyl-4-phenylpyridinium (MPP(+)).	Iron	96-100	interleukin 1 beta	Mus musculus	38-46	
23376588-9	2013	These results suggested that IL-1beta and TNF-alpha released by microglia, especially under the condition of iron load, might contribute to iron accumulation in VM neurons by upregulating IRP1 and hepcidin levels through reactive oxygen/nitrogen species production.	Iron	109-113	interleukin 1 beta	Mus musculus	29-37	
23376588-9	2013	These results suggested that IL-1beta and TNF-alpha released by microglia, especially under the condition of iron load, might contribute to iron accumulation in VM neurons by upregulating IRP1 and hepcidin levels through reactive oxygen/nitrogen species production.	Iron	140-144	interleukin 1 beta	Mus musculus	29-37