PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23326220-2 2013 Although the primary members of this family (RhoA, Rac and Cdc42) have different downstream effects on actin remodeling, the basic mechanism involves targeting to the plasma membrane and activation by GTP binding. Guanosine Triphosphate 201-204 AKT serine/threonine kinase 1 Homo sapiens 51-54