PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23308043-0 2012 Nicotine induces inhibitor of differentiation-1 in a Src-dependent pathway promoting metastasis and chemoresistance in pancreatic adenocarcinoma. Nicotine 0-8 inhibitor of DNA binding 1, HLH protein Homo sapiens 17-47 23308043-3 2012 Here, we show that stimulation of pancreatic cancer cells with nicotine concentrations that are within the range of human exposure results in activation of Src kinase, which facilitated the induction of the inhibitor of differentiation-1 (Id1) transcription factor. Nicotine 63-71 inhibitor of DNA binding 1, HLH protein Homo sapiens 207-237 23308043-3 2012 Here, we show that stimulation of pancreatic cancer cells with nicotine concentrations that are within the range of human exposure results in activation of Src kinase, which facilitated the induction of the inhibitor of differentiation-1 (Id1) transcription factor. Nicotine 63-71 inhibitor of DNA binding 1, HLH protein Homo sapiens 239-242 23308043-4 2012 Depletion of Id1 prevented nicotine-mediated induction of proliferation and invasion of pancreatic cancer cells, indicating that it is a major mediator of nicotine function. Nicotine 27-35 inhibitor of DNA binding 1, HLH protein Homo sapiens 13-16 23308043-4 2012 Depletion of Id1 prevented nicotine-mediated induction of proliferation and invasion of pancreatic cancer cells, indicating that it is a major mediator of nicotine function. Nicotine 155-163 inhibitor of DNA binding 1, HLH protein Homo sapiens 13-16