PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23267130-1 2013 BACKGROUND: Dihydroceramide desaturase 1 (DES) is the enzyme responsible for converting dihydroceramide into ceramide in the de novo sphingolipid biosynthesis pathway. Sphingolipids 133-145 delta 4-desaturase, sphingolipid 1 Homo sapiens 12-40