PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23161184-4	2013	Increased vascularization in chorioallantoic membrane assay, increased endothelial sprouting in rat aortic rings, and increased expression of CD31, E-selectin in endothelial cells suggested a possible proangiogenic effect of citrate.	Citric Acid	225-232	platelet and endothelial cell adhesion molecule 1	Rattus norvegicus	142-146	
23161184-4	2013	Increased vascularization in chorioallantoic membrane assay, increased endothelial sprouting in rat aortic rings, and increased expression of CD31, E-selectin in endothelial cells suggested a possible proangiogenic effect of citrate.	Citric Acid	225-232	selectin E	Rattus norvegicus	148-158	
23161184-5	2013	Upregulation of angiogenic factors such as vascular endothelial growth factor and fibroblast growth factor suggested that the effect of citrate involves modulation of expression of angiogenic growth factors.	Citric Acid	136-143	vascular endothelial growth factor A	Homo sapiens	43-77	
23161184-6	2013	LY 294002, an inhibitor of PI3K-Akt pathway, and wortmannin, an inhibitor of Akt pathway, reversed the effect of citrate in human umbilical vein endothelial cells.	Wortmannin	49-59	AKT serine/threonine kinase 1	Homo sapiens	77-80	
23161184-6	2013	LY 294002, an inhibitor of PI3K-Akt pathway, and wortmannin, an inhibitor of Akt pathway, reversed the effect of citrate in human umbilical vein endothelial cells.	Citric Acid	113-120	AKT serine/threonine kinase 1	Homo sapiens	77-80	
23161184-7	2013	Citrate induced significant upregulation and activation of Akt in endothelial cells.	Citric Acid	0-7	AKT serine/threonine kinase 1	Homo sapiens	59-62	
23161184-8	2013	Rapamycin, an inhibitor of mTOR, also reversed the effect of citrate in human umbilical vein endothelial cells and sprouting of aortic rings suggesting that the angiogenic effect of citrate involves activation of PI3K-Akt-mTOR pathway.	Sirolimus	0-9	mechanistic target of rapamycin kinase	Homo sapiens	27-31	
23161184-8	2013	Rapamycin, an inhibitor of mTOR, also reversed the effect of citrate in human umbilical vein endothelial cells and sprouting of aortic rings suggesting that the angiogenic effect of citrate involves activation of PI3K-Akt-mTOR pathway.	Sirolimus	0-9	AKT serine/threonine kinase 1	Homo sapiens	218-221	
23161184-8	2013	Rapamycin, an inhibitor of mTOR, also reversed the effect of citrate in human umbilical vein endothelial cells and sprouting of aortic rings suggesting that the angiogenic effect of citrate involves activation of PI3K-Akt-mTOR pathway.	Sirolimus	0-9	mechanistic target of rapamycin kinase	Homo sapiens	222-226	
23161184-8	2013	Rapamycin, an inhibitor of mTOR, also reversed the effect of citrate in human umbilical vein endothelial cells and sprouting of aortic rings suggesting that the angiogenic effect of citrate involves activation of PI3K-Akt-mTOR pathway.	Citric Acid	61-68	mechanistic target of rapamycin kinase	Homo sapiens	27-31	
23161184-8	2013	Rapamycin, an inhibitor of mTOR, also reversed the effect of citrate in human umbilical vein endothelial cells and sprouting of aortic rings suggesting that the angiogenic effect of citrate involves activation of PI3K-Akt-mTOR pathway.	Citric Acid	61-68	AKT serine/threonine kinase 1	Homo sapiens	218-221	
23161184-8	2013	Rapamycin, an inhibitor of mTOR, also reversed the effect of citrate in human umbilical vein endothelial cells and sprouting of aortic rings suggesting that the angiogenic effect of citrate involves activation of PI3K-Akt-mTOR pathway.	Citric Acid	61-68	mechanistic target of rapamycin kinase	Homo sapiens	222-226	
23161184-8	2013	Rapamycin, an inhibitor of mTOR, also reversed the effect of citrate in human umbilical vein endothelial cells and sprouting of aortic rings suggesting that the angiogenic effect of citrate involves activation of PI3K-Akt-mTOR pathway.	Citric Acid	182-189	mechanistic target of rapamycin kinase	Homo sapiens	27-31	
23161184-8	2013	Rapamycin, an inhibitor of mTOR, also reversed the effect of citrate in human umbilical vein endothelial cells and sprouting of aortic rings suggesting that the angiogenic effect of citrate involves activation of PI3K-Akt-mTOR pathway.	Citric Acid	182-189	AKT serine/threonine kinase 1	Homo sapiens	218-221	
23161184-8	2013	Rapamycin, an inhibitor of mTOR, also reversed the effect of citrate in human umbilical vein endothelial cells and sprouting of aortic rings suggesting that the angiogenic effect of citrate involves activation of PI3K-Akt-mTOR pathway.	Citric Acid	182-189	mechanistic target of rapamycin kinase	Homo sapiens	222-226