PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23095975-0	2012	Phagocytic NADPH oxidase links ARNO-Arf6 signaling pathway in glucose-stimulated insulin secretion from the pancreatic beta-cell.	Glucose	62-69	cytohesin 2	Rattus norvegicus	31-35	
23095975-0	2012	Phagocytic NADPH oxidase links ARNO-Arf6 signaling pathway in glucose-stimulated insulin secretion from the pancreatic beta-cell.	Glucose	62-69	ADP-ribosylation factor 6	Rattus norvegicus	36-40	
23095975-1	2012	BACKGROUND: Recent findings from our laboratory have demonstrated that glucose-stimulated insulin secretion (GSIS) involves interplay between a variety of small G proteins belonging to the Rho (e.g., Cdc42 and Rac1) and ADP-ribosylation factor (e.g., Arf6) subfamilies.	Glucose	71-78	cell division cycle 42	Rattus norvegicus	200-205	
23095975-1	2012	BACKGROUND: Recent findings from our laboratory have demonstrated that glucose-stimulated insulin secretion (GSIS) involves interplay between a variety of small G proteins belonging to the Rho (e.g., Cdc42 and Rac1) and ADP-ribosylation factor (e.g., Arf6) subfamilies.	Glucose	71-78	Rac family small GTPase 1	Rattus norvegicus	210-214	
23095975-1	2012	BACKGROUND: Recent findings from our laboratory have demonstrated that glucose-stimulated insulin secretion (GSIS) involves interplay between a variety of small G proteins belonging to the Rho (e.g., Cdc42 and Rac1) and ADP-ribosylation factor (e.g., Arf6) subfamilies.	Glucose	71-78	ADP-ribosylation factor 6	Rattus norvegicus	251-255	
23095975-2	2012	Using immunological, pharmacological and molecular biological approaches, we have also identified guanine nucleotide exchange factors (GEFs) for Rac1 (e.g., Tiam1) and Arf6 (e.g., ARNO) in clonal INS-1 832/13 cells, normal rat islets and human islets.	Guanine Nucleotides	98-116	Rac family small GTPase 1	Rattus norvegicus	145-149	
23095975-2	2012	Using immunological, pharmacological and molecular biological approaches, we have also identified guanine nucleotide exchange factors (GEFs) for Rac1 (e.g., Tiam1) and Arf6 (e.g., ARNO) in clonal INS-1 832/13 cells, normal rat islets and human islets.	Guanine Nucleotides	98-116	TIAM Rac1 associated GEF 1	Rattus norvegicus	157-162	
23095975-2	2012	Using immunological, pharmacological and molecular biological approaches, we have also identified guanine nucleotide exchange factors (GEFs) for Rac1 (e.g., Tiam1) and Arf6 (e.g., ARNO) in clonal INS-1 832/13 cells, normal rat islets and human islets.	Guanine Nucleotides	98-116	ADP-ribosylation factor 6	Rattus norvegicus	168-172	
23095975-2	2012	Using immunological, pharmacological and molecular biological approaches, we have also identified guanine nucleotide exchange factors (GEFs) for Rac1 (e.g., Tiam1) and Arf6 (e.g., ARNO) in clonal INS-1 832/13 cells, normal rat islets and human islets.	Guanine Nucleotides	98-116	cytohesin 2	Rattus norvegicus	180-184	
23095975-2	2012	Using immunological, pharmacological and molecular biological approaches, we have also identified guanine nucleotide exchange factors (GEFs) for Rac1 (e.g., Tiam1) and Arf6 (e.g., ARNO) in clonal INS-1 832/13 cells, normal rat islets and human islets.	Guanine Nucleotides	98-116	insulin 1	Rattus norvegicus	196-201	
23095975-5	2012	RESULTS: Our data suggested a marked inhibition by secinH3 of glucose-induced PLD activation, ERK1/2 phosphorylation and dephosphorylation of cofilin, suggesting that Arf6/ ARNO signaling mediates PLD, ERK1/2 and cofilin activation in beta-cells.	Glucose	62-69	cofilin 1	Homo sapiens	142-149	
23095975-5	2012	RESULTS: Our data suggested a marked inhibition by secinH3 of glucose-induced PLD activation, ERK1/2 phosphorylation and dephosphorylation of cofilin, suggesting that Arf6/ ARNO signaling mediates PLD, ERK1/2 and cofilin activation in beta-cells.	Glucose	62-69	ADP-ribosylation factor 6	Rattus norvegicus	167-171	
23095975-5	2012	RESULTS: Our data suggested a marked inhibition by secinH3 of glucose-induced PLD activation, ERK1/2 phosphorylation and dephosphorylation of cofilin, suggesting that Arf6/ ARNO signaling mediates PLD, ERK1/2 and cofilin activation in beta-cells.	Glucose	62-69	cytohesin 2	Rattus norvegicus	173-177	
23095975-5	2012	RESULTS: Our data suggested a marked inhibition by secinH3 of glucose-induced PLD activation, ERK1/2 phosphorylation and dephosphorylation of cofilin, suggesting that Arf6/ ARNO signaling mediates PLD, ERK1/2 and cofilin activation in beta-cells.	Glucose	62-69	mitogen activated protein kinase 3	Rattus norvegicus	202-208	
23095975-5	2012	RESULTS: Our data suggested a marked inhibition by secinH3 of glucose-induced PLD activation, ERK1/2 phosphorylation and dephosphorylation of cofilin, suggesting that Arf6/ ARNO signaling mediates PLD, ERK1/2 and cofilin activation in beta-cells.	Glucose	62-69	cofilin 1	Homo sapiens	213-220	
23095975-6	2012	In addition, secinH3 blocked glucose-induced Nox2 activation and associated ROS generation, thus placing Nox downstream to Arf6/ARNO signaling step.	Glucose	29-36	cytochrome b-245 beta chain	Rattus norvegicus	45-49	
23095975-6	2012	In addition, secinH3 blocked glucose-induced Nox2 activation and associated ROS generation, thus placing Nox downstream to Arf6/ARNO signaling step.	Glucose	29-36	ADP-ribosylation factor 6	Rattus norvegicus	123-127	
23095975-6	2012	In addition, secinH3 blocked glucose-induced Nox2 activation and associated ROS generation, thus placing Nox downstream to Arf6/ARNO signaling step.	Glucose	29-36	cytohesin 2	Rattus norvegicus	128-132	
23095975-6	2012	In addition, secinH3 blocked glucose-induced Nox2 activation and associated ROS generation, thus placing Nox downstream to Arf6/ARNO signaling step.	Reactive Oxygen Species	76-79	ADP-ribosylation factor 6	Rattus norvegicus	123-127