PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23064123-1 2012 A series of C7-substituted chromone (1-benzopyran-4-one) derivatives were synthesized and evaluated as inhibitors of recombinant human monoamine oxidase (MAO) A and B. Chromones 27-35 monoamine oxidase A Homo sapiens 135-166 23064123-4 2012 While the chromone derivatives also exhibit affinities for MAO-A, with IC(50) values ranging from 0.495 to 8.03 muM, they are selective for the MAO-B isoform. Chromones 10-18 monoamine oxidase A Homo sapiens 59-64 23064123-7 2012 With the aid of modeling studies, potential binding orientations and interactions of selected chromone derivatives in the MAO-A and -B active sites are examined. Chromones 94-102 monoamine oxidase A Homo sapiens 122-127