PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23038161-3 2012 To shorten beer maturation time, we constructed a self-cloning, bottom-fermenting yeast with low VDK production by integrating ILV5, a gene encoding a protein that metabolizes alpha-acetolactate and alpha-aceto-alpha-hydroxybutyrate (precursors of VDK). alpha-acetolactate 176-194 ketol-acid reductoisomerase Saccharomyces cerevisiae S288C 127-131