PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22985884-4	2012	Our study provides evidence that the seesaw effect applies to other beta-lactams and carbapenems of clinical use, including nafcillin (NAF), cefotaxime (CTX), amoxicillin-clavulanic (AMC), and imipenem (IMP), in heterogeneous DAP(r) MRSA strains but not in MRSA strains expressing homogeneous beta-lactam resistance.	beta-Lactams	68-80	death associated protein	Homo sapiens	226-229	
22985884-4	2012	Our study provides evidence that the seesaw effect applies to other beta-lactams and carbapenems of clinical use, including nafcillin (NAF), cefotaxime (CTX), amoxicillin-clavulanic (AMC), and imipenem (IMP), in heterogeneous DAP(r) MRSA strains but not in MRSA strains expressing homogeneous beta-lactam resistance.	beta-Lactams	68-79	death associated protein	Homo sapiens	226-229	
22985884-7	2012	In these models, DAP and a beta-lactam proved to be highly synergistic against both heterogeneous and homogeneous clinical DAP(r) MRSA strains.	beta-Lactams	27-38	death associated protein	Homo sapiens	123-126	
22985884-8	2012	Mechanistically, beta-lactams induced a reduction in the cell net positive surface charge, reverting the increased repulsion provoked by DAP alone, an effect that may favor the binding of DAP to the cell surface.	beta-Lactams	17-29	death associated protein	Homo sapiens	137-140	
22985884-8	2012	Mechanistically, beta-lactams induced a reduction in the cell net positive surface charge, reverting the increased repulsion provoked by DAP alone, an effect that may favor the binding of DAP to the cell surface.	beta-Lactams	17-29	death associated protein	Homo sapiens	188-191	
22985884-10	2012	Importantly, the combination of DAP and a beta-lactam prevented the selection of DAP(r) variants.	beta-Lactams	42-53	death associated protein	Homo sapiens	81-84