PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22956142-5 2012 Using Imatinib and BCR/ABL as a paradigm for a drug-target pair, we reported a retroviral vector-based screening strategy to identify the spectrum of resistance-conferring mutations, which has helped in designing the next-generation BCR/ABL inhibitors such as Nilotinib, Dasatinib, and Ponatinib. ponatinib 286-295 ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens 19-26 22956142-5 2012 Using Imatinib and BCR/ABL as a paradigm for a drug-target pair, we reported a retroviral vector-based screening strategy to identify the spectrum of resistance-conferring mutations, which has helped in designing the next-generation BCR/ABL inhibitors such as Nilotinib, Dasatinib, and Ponatinib. ponatinib 286-295 ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens 233-240