PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22923031-0 2012 Downregulation of matrix metalloproteinase-9 mRNA by valproic acid plays a role in inhibiting the shedding of MHC class I-related molecules A and B on the surface of human osteosarcoma cells. Valproic Acid 53-66 matrix metallopeptidase 9 Homo sapiens 18-44 22923031-1 2012 Valproic acid, a histone deacetylase inhibitor, increases the expression of cell surface MHC class I-related chain molecules (MICs) A and B (MICA and B) in osteosarcoma cells and decreases their secretion of soluble MICA and MICB, which are produced by the proteolytic cleavage of cell surface MICs. Valproic Acid 0-13 MHC class I polypeptide-related sequence A Homo sapiens 89-139 22923031-1 2012 Valproic acid, a histone deacetylase inhibitor, increases the expression of cell surface MHC class I-related chain molecules (MICs) A and B (MICA and B) in osteosarcoma cells and decreases their secretion of soluble MICA and MICB, which are produced by the proteolytic cleavage of cell surface MICs. Valproic Acid 0-13 MHC class I polypeptide-related sequence A Homo sapiens 141-145 22923031-1 2012 Valproic acid, a histone deacetylase inhibitor, increases the expression of cell surface MHC class I-related chain molecules (MICs) A and B (MICA and B) in osteosarcoma cells and decreases their secretion of soluble MICA and MICB, which are produced by the proteolytic cleavage of cell surface MICs. Valproic Acid 0-13 MHC class I polypeptide-related sequence A Homo sapiens 216-220 22923031-1 2012 Valproic acid, a histone deacetylase inhibitor, increases the expression of cell surface MHC class I-related chain molecules (MICs) A and B (MICA and B) in osteosarcoma cells and decreases their secretion of soluble MICA and MICB, which are produced by the proteolytic cleavage of cell surface MICs. Valproic Acid 0-13 MHC class I polypeptide-related sequence B Homo sapiens 225-229 22923031-1 2012 Valproic acid, a histone deacetylase inhibitor, increases the expression of cell surface MHC class I-related chain molecules (MICs) A and B (MICA and B) in osteosarcoma cells and decreases their secretion of soluble MICA and MICB, which are produced by the proteolytic cleavage of cell surface MICs. mics 126-130 MHC class I polypeptide-related sequence A Homo sapiens 141-145 22923031-3 2012 In this study, we investigated the involvement of MMP-2 and -9 in the inhibitory action of valproic acid (VPA) on the proteolytic cleavage of cell surface MICs using the U-2 OS and SaOS-2 osteosarcoma cell lines. Valproic Acid 91-104 matrix metallopeptidase 2 Homo sapiens 50-62 22923031-3 2012 In this study, we investigated the involvement of MMP-2 and -9 in the inhibitory action of valproic acid (VPA) on the proteolytic cleavage of cell surface MICs using the U-2 OS and SaOS-2 osteosarcoma cell lines. Valproic Acid 106-109 matrix metallopeptidase 2 Homo sapiens 50-62