PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22878868-0	2013	Nicotine treatment improves Toll-like receptor 2 and Toll-like receptor 9 responsiveness in active pulmonary sarcoidosis.	Nicotine	0-8	toll like receptor 2	Homo sapiens	28-48	
22878868-8	2013	Nicotine treatment was associated with restoration of TLR2 and TLR9 responsiveness, and expansion of Tregs, including the CD4 1 CD25 2 FoxP3 1 phenotype.	Nicotine	0-8	toll like receptor 2	Homo sapiens	54-58	
22878868-10	2013	CONCLUSIONS: Nicotine treatment in active pulmonary sarcoidosis was well tolerated and restored peripheral immune responsiveness to TLR2 and TLR9 agonists and expansion of FoxP3 1 Tregs, including a specific "preactivated" (CD25 2 ) phenotype.	Nicotine	13-21	toll like receptor 2	Homo sapiens	132-136