PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22843554-0 2012 Association between CASP8 and CASP10 polymorphisms and toxicity outcomes with platinum-based chemotherapy in Chinese patients with non-small cell lung cancer. Platinum 78-86 caspase 8 Homo sapiens 20-25 22843554-2 2012 In this study, we aimed to comprehensively assess single nucleotide polymorphisms (SNPs) of the caspase-8 (CASP8) and caspase-10 (CASP10) genes in relation to toxicity outcomes with first-line platinum-based chemotherapy in patients with advanced non-small cell lung cancer (NSCLC). Platinum 193-201 caspase 8 Homo sapiens 96-105 22843554-2 2012 In this study, we aimed to comprehensively assess single nucleotide polymorphisms (SNPs) of the caspase-8 (CASP8) and caspase-10 (CASP10) genes in relation to toxicity outcomes with first-line platinum-based chemotherapy in patients with advanced non-small cell lung cancer (NSCLC). Platinum 193-201 caspase 8 Homo sapiens 107-112 22843554-3 2012 We genotyped 13 tag SNPs of CASP8 and CASP10 in 663 patients with advanced NSCLC treated with platinum-based chemotherapy regimens. Platinum 94-102 caspase 8 Homo sapiens 28-33 22843554-9 2012 Our results provide novel evidence that polymorphisms in CASP8 and CASP10 may modulate toxicity outcomes in patients with advanced NSCLC treated with platinum-based chemotherapy. Platinum 150-158 caspase 8 Homo sapiens 57-62