PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22820510-1	2012	AIMS/HYPOTHESIS: Activation of the G protein-coupled receptor (GPR)40 by long-chain fatty acids potentiates glucose-stimulated insulin secretion (GSIS) from pancreatic beta cells, and GPR40 agonists are in clinical development for type 2 diabetes therapy.	long-chain fatty acids	73-95	free fatty acid receptor 1	Mus musculus	35-69	
22820510-1	2012	AIMS/HYPOTHESIS: Activation of the G protein-coupled receptor (GPR)40 by long-chain fatty acids potentiates glucose-stimulated insulin secretion (GSIS) from pancreatic beta cells, and GPR40 agonists are in clinical development for type 2 diabetes therapy.	Glucose	108-115	free fatty acid receptor 1	Mus musculus	35-69	
22820510-3	2012	This study aimed to determine the mechanisms of GPR40-dependent potentiation of GSIS by fatty acids.	Fatty Acids	88-99	free fatty acid receptor 1	Mus musculus	48-53	
22820510-9	2012	Exogenous DAG potentiates GSIS in both WT and Gpr40                            (-/-) islets.	Diglycerides	10-13	free fatty acid receptor 1	Mus musculus	46-51	
22820510-10	2012	Oleate induces PKD phosphorylation at residues Ser-744/748 and Ser-916 in WT but not Gpr40                            (-/-) islets.	Oleic Acid	0-6	protein kinase D1	Mus musculus	15-18	
22820510-10	2012	Oleate induces PKD phosphorylation at residues Ser-744/748 and Ser-916 in WT but not Gpr40                            (-/-) islets.	Serine	47-50	protein kinase D1	Mus musculus	15-18	
22820510-12	2012	CONCLUSIONS/INTERPRETATION: We conclude that the signalling cascade downstream of GPR40 activation by fatty acids involves activation of PKD1, F-actin depolymerisation and potentiation of second-phase insulin secretion.	Fatty Acids	102-113	free fatty acid receptor 1	Mus musculus	82-87	
22820510-12	2012	CONCLUSIONS/INTERPRETATION: We conclude that the signalling cascade downstream of GPR40 activation by fatty acids involves activation of PKD1, F-actin depolymerisation and potentiation of second-phase insulin secretion.	Fatty Acids	102-113	polycystin 1, transient receptor potential channel interacting	Mus musculus	137-141