PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22767591-8 2012 In these cells, IGF-I stimulation induced tyrosine phosphorylation of IGF-IR and IRS-1/2, but mutated IGF-IR failed to bind PI3K and to induce maximal phosphorylation of GSK3beta and cell proliferation in response to IGF-I. Tyrosine 42-50 insulin like growth factor 1 Homo sapiens 16-21 22767591-8 2012 In these cells, IGF-I stimulation induced tyrosine phosphorylation of IGF-IR and IRS-1/2, but mutated IGF-IR failed to bind PI3K and to induce maximal phosphorylation of GSK3beta and cell proliferation in response to IGF-I. Tyrosine 42-50 insulin like growth factor 1 Homo sapiens 70-75