PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22739161-6 2012 The positive cell number of activated caspase 3, caspase 8, caspase 9 and the levels of activated caspase 3, caspase 9, p-JNK, P38 increased after Jurkat cells were treated with GA. ROS, CaMKII, caspase 3, caspase 9, MAPKK, JNK1/2 and P38 inhibitors had some significant effect on GA-induced apoptosis. gambogic acid 178-180 mitogen-activated protein kinase 8 Homo sapiens 224-230 22739161-8 2012 It is concluded that GA induced apoptosis of Jurkat cells by activated caspases through activating of ROS-CaMKII-MAPKK-JNK/P38 pathway. gambogic acid 21-23 mitogen-activated protein kinase 8 Homo sapiens 119-122