PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22640737-2	2012	A second generation PARP inhibitor, GPI 15427, was administrated to mice to investigate the possible mechanisms underlying its neuroprotective effects after retinal I/R injury.	GPI 15427	36-45	poly (ADP-ribose) polymerase family, member 1	Mus musculus	20-24	
22640737-6	2012	GPI 15427 inhibited the retinal I/R-induced PARP activation and glial cell activation.	GPI 15427	0-9	poly (ADP-ribose) polymerase family, member 1	Mus musculus	44-48	
22640737-8	2012	I/R-induced PERK-eIF2alpha-CHOP activation and Bip over-expression were inhibited by GPI 15427, while it did not suppress I/R-induced CHOP over-expression and degeneration of retinal capillaries.	GPI 15427	85-94	eukaryotic translation initiation factor 2 alpha kinase 3	Mus musculus	12-16	
22640737-8	2012	I/R-induced PERK-eIF2alpha-CHOP activation and Bip over-expression were inhibited by GPI 15427, while it did not suppress I/R-induced CHOP over-expression and degeneration of retinal capillaries.	GPI 15427	85-94	eukaryotic translation initiation factor 2A	Mus musculus	17-26	
22640737-8	2012	I/R-induced PERK-eIF2alpha-CHOP activation and Bip over-expression were inhibited by GPI 15427, while it did not suppress I/R-induced CHOP over-expression and degeneration of retinal capillaries.	GPI 15427	85-94	DNA-damage inducible transcript 3	Mus musculus	27-31	
22640737-8	2012	I/R-induced PERK-eIF2alpha-CHOP activation and Bip over-expression were inhibited by GPI 15427, while it did not suppress I/R-induced CHOP over-expression and degeneration of retinal capillaries.	GPI 15427	85-94	heat shock protein 5	Mus musculus	47-50	
22640737-9	2012	Our results suggest that GPI 15427 inhibited retinal I/R-induced neurodegeneration and glial cell activation, and this was associated with an effect of the drug to suppress PERK-eIF2alpha-CHOP activation and Bip over-expression.	GPI 15427	25-34	eukaryotic translation initiation factor 2 alpha kinase 3	Mus musculus	173-177	
22640737-9	2012	Our results suggest that GPI 15427 inhibited retinal I/R-induced neurodegeneration and glial cell activation, and this was associated with an effect of the drug to suppress PERK-eIF2alpha-CHOP activation and Bip over-expression.	GPI 15427	25-34	eukaryotic translation initiation factor 2A	Mus musculus	178-187	
22640737-9	2012	Our results suggest that GPI 15427 inhibited retinal I/R-induced neurodegeneration and glial cell activation, and this was associated with an effect of the drug to suppress PERK-eIF2alpha-CHOP activation and Bip over-expression.	GPI 15427	25-34	DNA-damage inducible transcript 3	Mus musculus	188-192	
22640737-9	2012	Our results suggest that GPI 15427 inhibited retinal I/R-induced neurodegeneration and glial cell activation, and this was associated with an effect of the drug to suppress PERK-eIF2alpha-CHOP activation and Bip over-expression.	GPI 15427	25-34	heat shock protein 5	Mus musculus	208-211