PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2254323-7 1990 N alpha-Acetyl[D-Phe45, Arg47] hirudin45-65 (P53) emerged as a pure competitive inhibitor with a Ki = 2.8 +/- 0.9 nM and IC50 = 4.0 +/- 0.8 nM (human alpha-thrombin) and is designated as a "bifunctional" inhibitor. Cysteine 7-14 coagulation factor II, thrombin Homo sapiens 156-164