PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22477202-0	2012	Ursolic acid-induced apoptosis in K562 cells involving upregulation of PTEN gene expression and inactivation of the PI3K/Akt pathway.	ursolic acid	0-12	AKT serine/threonine kinase 1	Homo sapiens	121-124	
22477202-4	2012	Here, we demonstrated that UA was able to inhibit growth, induce apoptosis in a human chronic myelogenous leukemia cell line (K562 cells) via upregulation of PTEN gene expression, inhibit Akt kinase activity, change mitochondrial transmembrane potential and reduce the release of cytochrome c and the activity of caspases.	ursolic acid	27-29	AKT serine/threonine kinase 1	Homo sapiens	188-191	
22477202-5	2012	These results suggest that UA may elicit its strong antitumor effects via upregulation of the PTEN gene and inhibition of the PI3K/Akt pathway.	ursolic acid	27-29	AKT serine/threonine kinase 1	Homo sapiens	131-134