PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22459907-0 2012 Protease activated receptor-1 (PAR-1) mediated platelet aggregation is dependent on clopidogrel response. Clopidogrel 84-95 coagulation factor II thrombin receptor Homo sapiens 0-29 22459907-0 2012 Protease activated receptor-1 (PAR-1) mediated platelet aggregation is dependent on clopidogrel response. Clopidogrel 84-95 coagulation factor II thrombin receptor Homo sapiens 31-36 22459907-2 2012 Thrombin induces platelet aggregation by binding to protease activated receptor-1 (PAR-1), and inhibition of PAR-1 has been evaluated in patients treated with clopidogrel to reduce ischemic events after acute coronary syndromes. Clopidogrel 159-170 coagulation factor II thrombin receptor Homo sapiens 109-114 22459907-3 2012 Residual PAR-1 mediated platelet aggregation may be dependent on extent of clopidogrel response. Clopidogrel 75-86 coagulation factor II thrombin receptor Homo sapiens 9-14 22459907-9 2012 Addition of PAR-1 antiplatelet drugs may be most effective in patients with reduced clopidogrel response and high residual TRAP mediated platelet aggregation. Clopidogrel 84-95 coagulation factor II thrombin receptor Homo sapiens 12-17