PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22342521-1	2012	Hephaestin (Heph) is a ferroxidase protein that converts ferrous to ferric iron to facilitate cellular iron export by ferroportin.	Iron	75-79	hephaestin	Mus musculus	0-4	
22342521-3	2012	In mice, a combined systemic mutation of Heph and systemic knockout of Cp (Cp(-/-), Heph(sla/sla)) causes retinal iron accumulation and retinal degeneration, with features of human age-related macular degeneration; however, the role of Heph and Cp in the individual retinal cells is unclear.	Iron	114-118	hephaestin	Mus musculus	41-45	
22342521-3	2012	In mice, a combined systemic mutation of Heph and systemic knockout of Cp (Cp(-/-), Heph(sla/sla)) causes retinal iron accumulation and retinal degeneration, with features of human age-related macular degeneration; however, the role of Heph and Cp in the individual retinal cells is unclear.	Iron	114-118	hephaestin	Mus musculus	84-88	
22342521-5	2012	Loss of both Heph and Cp from RPE cells alone results in RPE cell iron accumulation and degeneration.	Iron	66-70	hephaestin	Mus musculus	13-17	
22342521-7	2012	Photoreceptor-specific Heph knockout indicates that the additional iron in the RPE cells does not result from loss of ferroxidases in the photoreceptors, and Cp and Heph play minor roles in photoreceptors.	Iron	67-71	hephaestin	Mus musculus	23-27	
22342521-9	2012	Cp and Heph are necessary for iron export from the retina but are not essential for iron import into the retina.	Iron	30-34	hephaestin	Mus musculus	7-11