PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22331493-0	2012	Sodium arsenite +- hyperthermia sensitizes p53-expressing human ovarian cancer cells to cisplatin by modulating platinum-DNA damage responses.	sodium arsenite	0-15	tumor protein p53	Homo sapiens	43-46	
22331493-4	2012	In this study, we examined the role of p53 status in EOC response to a novel combination of cisplatin, sodium arsenite, and hyperthermia.	sodium arsenite	103-118	tumor protein p53	Homo sapiens	39-42	
22331493-5	2012	Human EOC cells were treated with cisplatin +- 20muM sodium arsenite at 37 C or 39 C for 1 h. Sodium arsenite +- hyperthermia sensitized wild-type p53-expressing (A2780, A2780/CP70, OVCA 420, OVCA 429, and OVCA 433) EOC cells to cisplatin.	sodium arsenite	94-109	tumor protein p53	Homo sapiens	147-150	
22331493-7	2012	P53 small interfering RNA (siRNA) transfection abrogated sodium arsenite sensitization effect.	sodium arsenite	57-72	tumor protein p53	Homo sapiens	0-3	
22331493-9	2012	Cotreatment with sodium arsenite +- hyperthermia attenuated cisplatin-induced XPC in wild-type p53-expressing cells.	sodium arsenite	17-32	tumor protein p53	Homo sapiens	95-98	
22331493-10	2012	XPC siRNA transfection sensitized wild-type p53-expressing cells to cisplatin, suggesting that sodium arsenite +- hyperthermia attenuation of XPC is a mechanism by which wild-type p53-expressing cells are sensitized to cisplatin.	sodium arsenite	95-110	tumor protein p53	Homo sapiens	44-47	
22331493-10	2012	XPC siRNA transfection sensitized wild-type p53-expressing cells to cisplatin, suggesting that sodium arsenite +- hyperthermia attenuation of XPC is a mechanism by which wild-type p53-expressing cells are sensitized to cisplatin.	sodium arsenite	95-110	tumor protein p53	Homo sapiens	180-183	
22331493-11	2012	Hyperthermia +- sodium arsenite enhanced cellular and DNA accumulation of platinum in wild-type p53-expressing cells.	sodium arsenite	16-31	tumor protein p53	Homo sapiens	96-99	
22331493-13	2012	In conclusion, sodium arsenite +- hyperthermia sensitizes wild-type p53-expressing EOC cells to cisplatin by suppressing DNA repair protein XPC and increasing cellular and DNA platinum accumulation.	sodium arsenite	15-30	tumor protein p53	Homo sapiens	68-71