PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22308488-2	2012	We find that Ca(V) beta-subunits also determine channel regulation by the membrane phospholipid phosphatidylinositol 4,5-bisphosphate (PIP(2)).	phospholipid phosphatidylinositol 4,5-bisphosphate	83-133	carbonic anhydrase 5B	Homo sapiens	13-23	
22308488-3	2012	When Ca(V)1.3, -2.1, or -2.2 channels are cotransfected with the beta3-subunit, a cytosolic protein, they can be inhibited by activating a voltage-sensitive lipid phosphatase to deplete PIP(2).	piperidine	186-189	calcium voltage-gated channel subunit alpha1 D	Homo sapiens	5-13	
22308488-8	2012	In addition, the Lyn-beta3 subunit significantly decreased Ca(V) channel inhibition by PIP(2) depletion.	Phosphatidylinositol 4,5-Diphosphate	87-93	LYN proto-oncogene, Src family tyrosine kinase	Homo sapiens	17-20	
22308488-8	2012	In addition, the Lyn-beta3 subunit significantly decreased Ca(V) channel inhibition by PIP(2) depletion.	Phosphatidylinositol 4,5-Diphosphate	87-93	carbonic anhydrase 5A	Homo sapiens	59-64	
22308488-10	2012	Compared with expression with Ca(V) beta3-subunits alone, inhibition of Ca(V)2.2 channels by PIP(2) depletion could be significantly attenuated when beta2a was coexpressed with beta3.	Phosphatidylinositol 4,5-Diphosphate	93-99	carbonic anhydrase 5A	Homo sapiens	30-35	
22308488-10	2012	Compared with expression with Ca(V) beta3-subunits alone, inhibition of Ca(V)2.2 channels by PIP(2) depletion could be significantly attenuated when beta2a was coexpressed with beta3.	Phosphatidylinositol 4,5-Diphosphate	93-99	calcium voltage-gated channel subunit alpha1 B	Homo sapiens	72-80	
22308488-11	2012	Our data suggest that the Ca(V) currents in neurons would be regulated by membrane PIP(2) to a degree that depends on their endogenous beta-subunit combinations.	Phosphatidylinositol 4,5-Diphosphate	83-89	carbonic anhydrase 5A	Homo sapiens	26-31