PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22301607-8 2012 Inhibition of GEF-H1 by specific small interfering RNA or inactivation of Rho-associated kinase with Y-27632 not only significantly reduced LPS-induced p38 and extracellular signal-regulated kinase 1/2 (ERK1/2) activities but also blocked LPS-induced NF-kappaB translocation and activation, thereby inhibiting IL-6/TNF-alpha mRNA and protein productions. Y 27632 101-108 mitogen-activated protein kinase 3 Homo sapiens 203-209