PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22270849-0 2012 P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells. trichostatin A 61-75 tumor protein p53 Homo sapiens 0-3 22270849-0 2012 P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells. trichostatin A 77-80 tumor protein p53 Homo sapiens 0-3 22270849-8 2012 Characterizing the chromatin modulation around the p21(WAF1) promoter after TSA treatment using chromatin immunoprecipitation, we found (1) a release of HDAC1, (2) an increase of acetylated H4 binding, and (3) enhanced recruitment of p53. trichostatin A 76-79 tumor protein p53 Homo sapiens 234-237 22270849-12 2012 Furthermore, TSA-treated p53-mutant cell line U138 failed to show an induction in p21(WAF1), showed a deficient G2/M checkpoint, and underwent mitotic catastrophe. trichostatin A 13-16 tumor protein p53 Homo sapiens 25-28