PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22266344-0 2012 Regional c-Fos and FosB/DeltaFosB expression associated with chronic methamphetamine self-administration and methamphetamine-seeking behavior in rats. Methamphetamine 69-84 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 9-14 22266344-0 2012 Regional c-Fos and FosB/DeltaFosB expression associated with chronic methamphetamine self-administration and methamphetamine-seeking behavior in rats. Methamphetamine 109-124 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 9-14 22266344-6 2012 The results showed that acute METH produced a characteristic signature of Fos expression with elevations in striatal, cortical, and extended amygdala regions. Methamphetamine 30-34 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 74-77 22266344-7 2012 Importantly, rats with a 3-week history of METH self-administration displayed similar regional Fos expression to rats receiving METH for the first time. Methamphetamine 43-47 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 95-98 22266344-8 2012 Rats seeking, but not receiving, METH on the test day had augmented Fos in the lateral hypothalamus, septum, and vertical limb of the diagonal band of Broca, suggesting a primary role for these regions in METH-seeking behavior. Methamphetamine 33-37 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 68-71 22266344-12 2012 Overall, these results show persistent upregulated regional brain Fos and FosB/DeltaFosB expression with chronic METH self-administration and indicate a role for the lateral hypothalamus and lateral septum in METH-seeking behavior. Methamphetamine 113-117 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 66-69