PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22265823-0 2012 Involvement of activation of PI3K/Akt pathway in the protective effects of puerarin against MPP+-induced human neuroblastoma SH-SY5Y cell death. puerarin 75-83 AKT serine/threonine kinase 1 Homo sapiens 34-37 22265823-3 2012 The presence of PI3K inhibitor LY294002 completely blocked puerarin-induced activation of Akt phosphorylation. puerarin 59-67 AKT serine/threonine kinase 1 Homo sapiens 90-93 22265823-8 2012 Collectively, these data suggest that the activation of PI3K/Akt pathway is involved in the protective effect of puerarin against MPP(+)-induced neuroblastoma SH-SY5Y cell death through inhibiting nuclear p53 accumulation and subsequently caspase-3-dependent PCD. puerarin 113-121 AKT serine/threonine kinase 1 Homo sapiens 61-64