PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22244335-1 2012 Histone H2B ubiquitylation is a transcription-dependent modification that not only regulates nucleosome dynamics but also controls the trimethylation of histone H3 on lysine 4 by promoting ubiquitylation of Swd2, a component of both the histone methyltransferase COMPASS complex and the cleavage and polyadenylation factor(CPF). Lysine 167-173 H2B clustered histone 21 Homo sapiens 8-11