PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22137642-2 2010 Several factors are involved in this regulatory mechanism, such as serine/arginine-rich (SR) proteins, the Cdc2-like kinase (Clk) family, the dual-specificity tyrosine phosphorylation regulated kinases, the SR protein kinases (SRPK) 1 and 2, the protein kinase B (PKB,Akt), and the DNA topoisomerase I (DNA topo I). Tyrosine 159-167 AKT serine/threonine kinase 1 Homo sapiens 264-271