PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22132761-3 2012 Here we report a novel assay for Asp isomerization by isotopic labeling with (18)O via a two-step process: the isoAsp peptide is first specifically methylated by protein isoaspartate methyltransferase (PIMT, EC 2.1.1.77) to the corresponding methyl ester, which is subsequently hydrolyzed in (18)O-water to regenerate isoAsp. Aspartic Acid 33-36 protein-L-isoaspartate (D-aspartate) O-methyltransferase Homo sapiens 202-206