PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22108347-0 2012 Ursolic acid suppresses IL-6 induced C-reactive protein expression in HepG2 and protects HUVECs from injury induced by CRP. ursolic acid 0-12 interleukin 6 Homo sapiens 24-28 22108347-1 2012 OBJECTIVE: To investigate the inhibitory effects of ursolic acid (UA) on the expression of C-reactive protein (CRP) induced by IL-6 in HepG2 cells and the protective effects on the CRP-induced injury to human umbilical vein endothelial cells (HUVECs). ursolic acid 52-64 interleukin 6 Homo sapiens 127-131 22108347-1 2012 OBJECTIVE: To investigate the inhibitory effects of ursolic acid (UA) on the expression of C-reactive protein (CRP) induced by IL-6 in HepG2 cells and the protective effects on the CRP-induced injury to human umbilical vein endothelial cells (HUVECs). ursolic acid 66-68 interleukin 6 Homo sapiens 127-131 22108347-7 2012 RESULT: IL-6 can significantly increase CRP protein and mRNA expression in HepG2 cells, and this effect of IL-6 can be decreased by UA (6.25, 12.5, 25 mumol/L) markedly in a dose-dependent manner. ursolic acid 132-134 interleukin 6 Homo sapiens 107-111 22108347-10 2012 CONCLUSION: UA can reduce the over expression of CRP in HepG2 cells induced by IL-6 and inhibit the increased expression of VCAM-1 and LOX-1 in HUVECs caused by CRP. ursolic acid 12-14 interleukin 6 Homo sapiens 79-83