PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22106281-1 2011 We have discovered that the enzyme phospholipase D2 (PLD2) binds directly to the small GTPase Rac2, resulting in PLD2 functioning as a guanine nucleotide exchange factor (GEF), because it switches Rac2 from the GDP-bound to the GTP-bound states. Guanosine Diphosphate 211-214 Ras protein specific guanine nucleotide releasing factor 1 Homo sapiens 135-169 22106281-1 2011 We have discovered that the enzyme phospholipase D2 (PLD2) binds directly to the small GTPase Rac2, resulting in PLD2 functioning as a guanine nucleotide exchange factor (GEF), because it switches Rac2 from the GDP-bound to the GTP-bound states. Guanosine Diphosphate 211-214 Ras protein specific guanine nucleotide releasing factor 1 Homo sapiens 171-174