PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21999473-2 2011 The new antidepressant agomelatine is an agonist of melatonergic MT1/MT2 receptors as well as an antagonist of serotonergic 5-HT2C receptors. agomelatine 23-34 metallothionein 1I, pseudogene Homo sapiens 65-68 21999473-2 2011 The new antidepressant agomelatine is an agonist of melatonergic MT1/MT2 receptors as well as an antagonist of serotonergic 5-HT2C receptors. agomelatine 23-34 metallothionein 2A Homo sapiens 69-72 21999473-5 2011 RESULTS: Recent data on the effects of agomelatine on cellular processes involved in antidepressant mechanisms have shown that the drug is able to increase the expression of brain-derived neurotrophic factor in prefrontal cortex and hippocampus, as well as the expression of activity-regulated cytoskeleton associated protein (Arc) in the prefrontal cortex. agomelatine 39-50 brain derived neurotrophic factor Homo sapiens 174-207 21999473-5 2011 RESULTS: Recent data on the effects of agomelatine on cellular processes involved in antidepressant mechanisms have shown that the drug is able to increase the expression of brain-derived neurotrophic factor in prefrontal cortex and hippocampus, as well as the expression of activity-regulated cytoskeleton associated protein (Arc) in the prefrontal cortex. agomelatine 39-50 activity regulated cytoskeleton associated protein Homo sapiens 275-325