PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21983942-2 2011 Here we show that sealing BBB TJs by ectopic tetracycline-regulated expression of the TJ protein claudin-1 in Tie-2 tTA//TRE-claudin-1 double transgenic C57BL/6 mice had no influence on immune cell trafficking across the BBB during EAE and furthermore did not influence the onset and severity of the first clinical disease episode. Tetracycline 45-57 TEK receptor tyrosine kinase Mus musculus 110-115