PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21975240-2 2011 The more reactive conformation is the homocysteine thiolactone (HcyT), product to the nonspecific action of methionyl-tRNA synthetase, which is incorporated into proteins by disulfide bonds (S-homocysteinilation) or amide bonds (N-homocysteinilation) affecting protein structure and function leading to cell toxicity, autoimmune responses and atherogenesis. Homocysteine 38-50 methionyl-tRNA synthetase 1 Homo sapiens 108-133